This ebook, Bacterial Therapy of Cancer: Methods and Protocols (PDF) explores the evolution of bacterial cancer therapy and describes the modern techniques used in therapy today. The chapters in this volume cover a broad range of topics such as the development of tumor-targeting Salmonella typhimurium A1-R, a microfluidic device for precise quantification of the interactions between tumor-targeting bacteria and tumor tissue, methods to achieve remote-control of therapeutic gene expression in tumor-targeting bacteria, non-invasive in vivo imaging of bacteria-mediated cancer therapy using bio-luminescent bacteria, and cell-cycle decoy of cancer cells resistant to cytotoxic drugs to drug sensitivity by S. typhimurium A1-R. This book concludes with a chapter on the future potential of bacterial therapy of cancer. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, readily reproducible and step-by-step laboratory protocols, and tips on troubleshooting and avoiding known problems and pitfalls.
Thorough and informative, Bacterial Therapy of Cancer: Methods and Protocols is a very valuable resource for anyone who is interested in cancer and bacterial therapy.